Peripheral nerve regeneration

Neurosci Res Suppl. 1990;13:S157-64. doi: 10.1016/0921-8696(90)90045-5.


Schwann cell basal laminae were demonstrated to serve as efficient conduits for the growth of regenerating axons in frozen nerve grafts, and in in situ freezing experiments. Regenerating axonal sprouts usually emanated from the first node of Ranvier proximal to the site of damage, and grew out along the inner surface of the basal lamina. Early growth cones contained numerous clear vesicles of about 50 nm in diameter.

MeSH terms

  • Animals
  • Axons / physiology
  • Freezing
  • Mice
  • Microscopy, Electron
  • Nerve Regeneration*
  • Peripheral Nerves / physiology*
  • Ranvier's Nodes / physiology
  • Replantation
  • Sciatic Nerve / physiology
  • Sciatic Nerve / surgery
  • Sciatic Nerve / ultrastructure
  • Time Factors