Correlation of 111indium WBC scintigraphy with ultrasound in the detection and assessment of inflammatory bowel disease

Clin Radiol. 1990 Dec;42(6):410-3. doi: 10.1016/s0009-9260(05)80896-7.


111Indium (111In) WBC scintigraphy is an accurate method of assessing the extent of inflammatory bowel disease. A prospective study was performed to determine the correlation of ultrasound scanning with 111In WBC scintigraphy in the assessment of inflammatory bowel disease. Eighty-three indium and ultrasound scans were performed in 57 patients. Forty-six patients had Crohn's disease and 11 patients had ulcerative colitis. The site extent of abnormality and the appearance of the bowel were recorded and compared to the findings on indium scintigraphy. Ultrasound detected 84% of indium-positive sites. If the rectum was excluded, sensitivity of detection rose to 91%. Three percent of indium-negative sites were positive on ultrasound.

Publication types

  • Clinical Trial

MeSH terms

  • Colitis, Ulcerative / diagnosis*
  • Colitis, Ulcerative / diagnostic imaging
  • Crohn Disease / diagnosis*
  • Crohn Disease / diagnostic imaging
  • Granulocytes
  • Humans
  • Indium Radioisotopes
  • Organometallic Compounds
  • Prospective Studies
  • Radionuclide Imaging
  • Tropolone / analogs & derivatives
  • Ultrasonography


  • Indium Radioisotopes
  • Organometallic Compounds
  • indium tris(tropolonate)
  • Tropolone