Effect of intrarectal povidone-iodine in the incidence of infectious complications after transrectal prostatic biopsy

Arch Esp Urol. 2012 May;65(4):463-6.
[Article in En, Spanish]


Objectives: To assess the incidence of genitourinary infections associated with transrectal ultrasound-guided prostate biopsy (TRUS-BX) using endorectal povidone-iodine gel as a bactericidal agent.

Methods: We prospectively studied a total of 530 patients who were given 30g of 10% povidone-iodine intrarectally before TRUS-BX. Each patient received antibiotic prophylaxis with ciprofloxacin, starting the previous day (1g/day x 3 days), as well as cleansing enemas.

Results: One patient (0.20%) presented with an E. coli acute bacterial epididymitis after biopsy.

Conclusions: In our study, the intrarectal use of 10% povidone-iodine gel in TRUS-BX is associated with a much lower rate of infectious complications compared to those described in recent literature.

Publication types

  • Evaluation Study

MeSH terms

  • Administration, Rectal
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Infective Agents, Local / administration & dosage*
  • Bacterial Infections / epidemiology
  • Bacterial Infections / prevention & control*
  • Biopsy, Needle / adverse effects*
  • Ciprofloxacin / therapeutic use
  • Humans
  • Incidence
  • Male
  • Male Urogenital Diseases / epidemiology
  • Male Urogenital Diseases / prevention & control*
  • Middle Aged
  • Povidone-Iodine / administration & dosage*
  • Prospective Studies
  • Prostate / pathology
  • Prostatic Neoplasms / pathology
  • Ultrasonography, Interventional


  • Anti-Infective Agents, Local
  • Ciprofloxacin
  • Povidone-Iodine