BRAF Inhibition in Refractory Hairy-Cell Leukemia

N Engl J Med. 2012 May 24;366(21):2038-40. doi: 10.1056/NEJMc1202124.

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Humans
  • Indoles / therapeutic use*
  • Leukemia, Hairy Cell / drug therapy*
  • Leukemia, Hairy Cell / genetics
  • Male
  • Middle Aged
  • Mutation
  • Proto-Oncogene Proteins B-raf / antagonists & inhibitors*
  • Proto-Oncogene Proteins B-raf / genetics
  • Remission Induction
  • Sulfonamides / therapeutic use*
  • Vemurafenib

Substances

  • Antineoplastic Agents
  • Indoles
  • Sulfonamides
  • Vemurafenib
  • BRAF protein, human
  • Proto-Oncogene Proteins B-raf