[Evaluation study of clinical and neurobiological efficacy of EMDR in patients suffering from post-traumatic stress disorder]

Riv Psichiatr. 2012 Mar-Apr;47(2 Suppl):12-5. doi: 10.1708/1071.11733.
[Article in Italian]


Strong evidences support use of EMDR in patients suffering from post-traumatic stress disorder (PTSD).

Aim: To evaluate clinical and neurobiological-structural efficacy of EMDR on drug-naïve PTSD without comorbidity.

Materials and methods: We made clinical evaluation and hippocampal volume measurement by MRI on 29 subjects suffering from PTSD and on 30 healthy control-subjects. Then, patients were treated with EMDR and after three months of psychotherapy the clinical evaluation and the MRI exam were replied.

Results and discussion: Our results demonstrated that the diagnosis of PTSD was no more possible on all the patients who terminated the psychotherapy (n=18). At the same time, all the patients showed an average increase of 6% in hippocampal volumes.

Conclusions: Our reaserach suggests that EMDR treatment correlates not only with a significant improvement of symptoms of PTSD, but also with a significant increase of hippocampal volumes.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Eye Movement Desensitization Reprocessing*
  • Female
  • Hippocampus / anatomy & histology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Organ Size
  • Stress Disorders, Post-Traumatic / diagnosis
  • Stress Disorders, Post-Traumatic / therapy*