RNA-directed DNA methylation: getting a grip on mechanism

Judith Bender

doi:10.1016/j.cub.2012.04.010

RNA-directed DNA methylation: getting a grip on mechanism

Curr Biol. 2012 May 22;22(10):R400-1. doi: 10.1016/j.cub.2012.04.010.

Author

Judith Bender¹

Affiliation

¹ Brown University, MCB Department, Providence, RI 02912, USA. judith_bender@brown.edu

PMID: 22625855
DOI: 10.1016/j.cub.2012.04.010

Abstract

Small RNAs guide repressive chromatin modifications to regions of the genome containing transposons and repeats. An Arabidopsis genetic screen reveals that the guidance machinery includes a novel ATPase complex that could act as a dynamic molecular gripper.

Publication types

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MeSH terms

Adenosine Triphosphatases / metabolism*
Arabidopsis / genetics*
Arabidopsis Proteins / metabolism*
Chromosomal Proteins, Non-Histone / metabolism*
DNA Methylation / physiology*

Substances

Arabidopsis Proteins
Chromosomal Proteins, Non-Histone
DMS3 protein, Arabidopsis
Adenosine Triphosphatases
MORC6 protein, Arabidopsis