Delayed presentation: negative pressure pulmonary hemorrhage

J Clin Anesth. 2012 Sep;24(6):490-3. doi: 10.1016/j.jclinane.2012.02.001. Epub 2012 May 22.


Negative pressure pulmonary hemorrhage (NPPH) is a rare, life-threatening complication that develops after an acute upper airway obstruction. A 26 year old, healthy African-American man with no underlying lung disease developed negative pressure pulmonary edema and subsequently NPPH during recovery from general anesthesia for elective spine surgery. Diagnostic bronchoscopy confirmed an alveolar source of the bleeding. Clinical improvement was quick with supportive care in the medical intensive care unit.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Airway Obstruction / complications*
  • Anesthesia, General / methods
  • Bronchoscopy / methods
  • Elective Surgical Procedures / methods
  • Hemorrhage / etiology*
  • Humans
  • Male
  • Pulmonary Alveoli / pathology
  • Pulmonary Edema / etiology*
  • Spinal Injuries / surgery
  • Time Factors