Evasion from NK cell-mediated immune responses by HIV-1

Microbes Infect. 2012 Sep;14(11):904-15. doi: 10.1016/j.micinf.2012.05.001. Epub 2012 May 21.


Human immunodeficiency virus type 1 (HIV-1) mostly owes its success to its ability to evade host immune responses. Understanding viral immune escape mechanisms is a prerequisite to improve future HIV-1 vaccine design. This review focuses on the strategies that HIV-1 has evolved to evade recognition by natural killer (NK) cells.

Publication types

  • Review

MeSH terms

  • HIV Infections / immunology*
  • HIV Infections / virology
  • HIV-1 / immunology*
  • Host-Pathogen Interactions
  • Humans
  • Immunity, Innate
  • Killer Cells, Natural / immunology*
  • Viral Vaccines / immunology*


  • Viral Vaccines