Reproducible vapor-time profiles using solid-phase microextraction with an externally sampled internal standard

J Chromatogr A. 2012 Jun 29:1244:28-36. doi: 10.1016/j.chroma.2012.04.068. Epub 2012 May 3.

Abstract

Determination of the dynamic nature of vapor/odor release has application in a wide variety of systems. This study applies automated solid-phase microextraction (SPME) utilizing an externally sampled internal standard (ESIS) to determine the vapor-time profile of odor delivery devices for three classes of explosive compounds. The profiles of delivery systems for target odorants 2,4-dinitrotoluene (2,4-DNT), 2-ethyl-1-hexanol (2-EH), and triacetone triperoxide (TATP) as canine training aids were compared over a period of 70 h. Strategies for evaluating the vapor-time profile of components with widely differing volatility are considered. An approach to quantifying the vapor concentration is described. The differences in the vapor-time profiles are examined and suggestions for selecting the best representative odor delivery technique are outlined.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Dimethylpolysiloxanes
  • Dinitrobenzenes / analysis
  • Gas Chromatography-Mass Spectrometry
  • Heterocyclic Compounds, 1-Ring / analysis
  • Hexanols / analysis
  • Odorants / analysis*
  • Peroxides / analysis
  • Reference Standards
  • Solid Phase Microextraction / methods*
  • Solid Phase Microextraction / standards*
  • Temperature

Substances

  • Dimethylpolysiloxanes
  • Dinitrobenzenes
  • Heterocyclic Compounds, 1-Ring
  • Hexanols
  • Peroxides
  • triacetone triperoxide
  • baysilon
  • 2,4-dinitrotoluene
  • 2-ethylhexanol