Abstract
This report describes a previously unrecognized role for bacterial surface layers as barriers that confer protection against antimicrobial peptides. As antimicrobial peptides exist in natural environments, S-layers may provide a bacterial survival mechanism that has been selected for through evolution.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antimicrobial Cationic Peptides / pharmacology*
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Biological Evolution*
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Caulobacter crescentus / drug effects
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Caulobacter crescentus / metabolism
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Caulobacter crescentus / ultrastructure*
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Cell Wall / drug effects
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Cell Wall / metabolism*
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Membrane Glycoproteins / metabolism*
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Microscopy, Electron
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Species Specificity
Substances
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Antimicrobial Cationic Peptides
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Membrane Glycoproteins
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S-layer proteins