Gametogenesis in a dish

Cell Res. 2012 Oct;22(10):1422-5. doi: 10.1038/cr.2012.84. Epub 2012 May 29.


Recent progress in the induced pluripotent stem cell (iPSC) field as well as the establishment of germline stem cell isolation and culture methodologies may provide an in vitro platform for the study of physiological and pathological human gamete development and open new avenues for cell replacement-based personalized treatment of infertility.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Embryonic Stem Cells / cytology
  • Female
  • Gametogenesis / physiology*
  • Humans
  • Induced Pluripotent Stem Cells / cytology*
  • Induced Pluripotent Stem Cells / transplantation
  • Infertility / therapy
  • Male
  • Models, Biological