Elevated troponin T levels in a female carrier of Duchenne muscular dystrophy with normal coronary angiogram: a case report and review of the literature

Acta Cardiol. 2012 Apr;67(2):253-6. doi: 10.1080/ac.67.2.2154220.


We present the case of a 48-year-old female carrier of Duchenne muscular dystrophy (DMD) with repeatedly documented levels of elevated troponin T without arguments for cardiac ischaemia. Elevated levels of troponin T are frequently reported in DMD patients and may function as a useful cardiac index to assess dystrophic degeneration of the myocardium in a subclinical stage. Cardiac troponins may help the clinician to diagnose myocardial damage in a very early stage of cardiac impairment independently from skeletal muscle degeneration.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Biomarkers / blood
  • Coronary Angiography
  • Female
  • Heart Diseases / blood*
  • Heart Diseases / diagnosis
  • Heterozygote
  • Humans
  • Middle Aged
  • Muscular Dystrophy, Duchenne / blood*
  • Muscular Dystrophy, Duchenne / genetics*
  • Myocardium / metabolism
  • Myocardium / pathology
  • Troponin T / blood*


  • Biomarkers
  • Troponin T