Strikingly low prevalence of atrial fibrillation in elderly Tanzanians

J Am Geriatr Soc. 2012 Jun;60(6):1135-40. doi: 10.1111/j.1532-5415.2012.03963.x. Epub 2012 May 30.

Abstract

Objectives: To determine the prevalence of atrial fibrillation (AF) in individuals aged 70 and older in a rural African community.

Design: Community-based cross-sectional survey.

Setting: A demographic surveillance site (DSS) within the rural Hai district of northern Tanzania.

Participants: Approximately one-quarter (N = 2,232) of the population aged 70 and older of the DSS.

Measurements: Participants were screened for AF using 12-lead electrocardiography; demographic and 1-year mortality data were collected; and functional status, body mass index, and blood pressure were recorded. The sex-specific prevalence of AF in each 5-year age band was determined.

Results: Fifteen of 2,232 participants (12 women, 3 men) had AF, giving a crude prevalence rate of 0.67% (95% confidence interval (CI) = 0.33-1.01) and an age-adjusted prevalence of 0.64% (95% CI = 0.31-0.97). Prevalence was 0.96% (95% CI = 0.42-1.49) in women and 0.31% (95% CI = -0.04 to 1.24) in men. Prevalence increased with age, from 0.46% (95% CI = 0.01-0.90) in those aged 70-74-1.30% (95% CI = 0.17-2.42) in those aged 85 and older. One-year mortality was 50% in women and 66.6% in men.

Conclusions: This is the first published community-based AF prevalence study from sub-Saharan Africa. The prevalence rate of AF is strikingly lower than in other elderly populations studied, yet the 1-year mortality rate was exceedingly high.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Atrial Fibrillation / epidemiology*
  • Blood Pressure
  • Body Mass Index
  • Case-Control Studies
  • Cross-Sectional Studies
  • Electrocardiography
  • Female
  • Humans
  • Male
  • Mass Screening
  • Population Surveillance
  • Prevalence
  • Tanzania / epidemiology