A case series of the management of symptomatic azole-resistant candida

Int J STD AIDS. 2012 May;23(5):375-6. doi: 10.1258/ijsa.2009.009441.

Abstract

Patients with symptomatic azole-resistant Candida albicans or non-albicans candida are difficult to manage. Treatment is largely anecdotal due to the relatively small number of patients. We present six case reports which highlight our own observation in clinical practice including four patients who were treated successfully with topical amphotericin B/flucytosine vaginal gel for 14 days (Stoke-on-Trent formula).

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Amphotericin B / administration & dosage*
  • Antifungal Agents / administration & dosage*
  • Antifungal Agents / pharmacology
  • Azoles / pharmacology
  • Candida albicans / drug effects*
  • Candida albicans / isolation & purification
  • Candidiasis, Vulvovaginal / drug therapy*
  • Candidiasis, Vulvovaginal / microbiology*
  • Drug Resistance, Fungal*
  • Female
  • Flucytosine / administration & dosage*
  • Humans
  • Middle Aged
  • Treatment Outcome
  • Vaginal Creams, Foams, and Jellies / administration & dosage
  • Young Adult

Substances

  • Antifungal Agents
  • Azoles
  • Vaginal Creams, Foams, and Jellies
  • Amphotericin B
  • Flucytosine