Simple Ways to Measure Behavioral Responses of Drosophila to Stimuli and Use of These Methods to Characterize a Novel Mutant

PLoS One. 2012;7(5):e37495. doi: 10.1371/journal.pone.0037495. Epub 2012 May 23.


The behavioral responses of adult Drosophila fruit flies to a variety of sensory stimuli--light, volatile and non-volatile chemicals, temperature, humidity, gravity, and sound--have been measured by others previously. Some of those assays are rather complex; a review of them is presented in the Discussion. Our objective here has been to find out how to measure the behavior of adult Drosophila fruit flies by methods that are inexpensive and easy to carry out. These new assays have now been used here to characterize a novel mutant that fails to be attracted or repelled by a variety of sensory stimuli even though it is motile.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Behavior, Animal / physiology*
  • Chemotaxis / physiology*
  • Data Collection / methods
  • Drosophila / genetics
  • Drosophila / physiology*
  • Gravitation
  • Humidity
  • Light*
  • Mutagenesis
  • Sensation / physiology*
  • Smell / physiology*
  • Taste / physiology*
  • Temperature