Bacterial meningitis and pneumococcal serotype distribution in children in cameroon

Pediatr Infect Dis J. 2012 Oct;31(10):1084-7. doi: 10.1097/INF.0b013e318260552d.

Abstract

Acute bacterial meningitis causes a substantial number of deaths in Cameroon. Among 170 children with acute meningitis, 112 were positive for a bacterial pathogen when tested using polymerase chain reaction amplification, and Streptococcus pneumoniae accounted for 57.1% of cases. Pneumococcal serotype coverage by 13-valent pneumococcal conjugate vaccine was 62.1%. This study shows that in Cameroon, 13-valent pneumococcal conjugate vaccine coverage is less than what is estimated for other African countries.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Cameroon / epidemiology
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Male
  • Meningitis, Bacterial / epidemiology*
  • Meningitis, Bacterial / microbiology*
  • Multicenter Studies as Topic
  • Pneumococcal Vaccines / immunology
  • Polymerase Chain Reaction
  • Prospective Studies
  • Serotyping
  • Streptococcus pneumoniae / classification*
  • Streptococcus pneumoniae / isolation & purification*

Substances

  • 13-valent pneumococcal vaccine
  • Pneumococcal Vaccines