Abstract
Reaction-based fluorescent probes for monoamine oxidases A and B are developed based on a new two-photon absorbing compound and its precursor. The probes show turn-on fluorescence response to the enzymes owing to the two-photon absorbing compound produced by the enzymatic activity, as monitored by one- as well as two-photon microscopy for the first time.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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2-Naphthylamine / analogs & derivatives*
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2-Naphthylamine / chemistry
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Acrylonitrile / analogs & derivatives*
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Acrylonitrile / chemistry
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Animals
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Cell Line, Tumor
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Fluorescent Dyes / chemistry*
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Microscopy, Fluorescence
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Monoamine Oxidase / analysis
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Monoamine Oxidase / metabolism*
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Photons*
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Rats
Substances
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Fluorescent Dyes
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2-Naphthylamine
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Monoamine Oxidase
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Acrylonitrile