Emergence and characterisation of vanB vancomycin-resistant Enterococcus faecalis in Rio de Janeiro, Brazil

Mem Inst Oswaldo Cruz. 2012 Jun;107(4):557-60. doi: 10.1590/s0074-02762012000400020.

Abstract

Here we describe the detection and characterisation of three isolates of vancomycin-resistant VanB-type Enterococcus faecalis. Sequence analysis suggested that these isolates harboured the vanB1 gene. The isolates were susceptible to the majority of antimicrobial agents tested, with the exception of chloramphenicol, erythromycin and vancomycin, and showed distinct profiles of high-level resistance to aminoglycosides. Analysis of the clonal relatedness of the vanB E. faecalis isolates showed similar pulsed-field gel electrophoresis profiles. To our knowledge, this is the first report of the occurrence of enterococcal strains carrying vanB genes in Brazil.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / genetics*
  • Brazil
  • Cross Infection / microbiology*
  • Disk Diffusion Antimicrobial Tests
  • Electrophoresis, Gel, Pulsed-Field
  • Enterococcus faecalis / drug effects
  • Enterococcus faecalis / genetics*
  • Gram-Positive Bacterial Infections / microbiology*
  • Humans
  • Vancomycin Resistance / genetics*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • VanB protein, Enterococcus