Effects of flecainide therapy on inappropriate shocks and arrhythmias in catecholaminergic polymorphic ventricular tachycardia

J Electrocardiol. 2012 Nov-Dec;45(6):736-8. doi: 10.1016/j.jelectrocard.2012.05.002. Epub 2012 Jun 4.

Abstract

We report the case of a child with catecholaminergic polymorphic ventricular tachycardia, who had inappropriate electric shocks by an implantable cardioverter defibrillator and from recurrence of arrhythmias despite an appropriate β-blocking treatment. An additional treatment by flecainide completely suppressed inappropriate shocks due to sinusal tachycardia and ventricular tachyarrhythmias. We briefly discuss the potentially interesting effect of flecainide in this specific arrhythmia.

MeSH terms

  • Anti-Arrhythmia Agents / therapeutic use
  • Child, Preschool
  • Defibrillators, Implantable / adverse effects*
  • Equipment Failure*
  • Flecainide / therapeutic use*
  • Humans
  • Male
  • Pacemaker, Artificial
  • Polymorphic Catecholaminergic Ventricular Tachycardia
  • Secondary Prevention
  • Tachycardia, Ventricular / diagnosis
  • Tachycardia, Ventricular / etiology*
  • Tachycardia, Ventricular / prevention & control*
  • Treatment Outcome

Substances

  • Anti-Arrhythmia Agents
  • Flecainide