Touraine-Solente-Gole' syndrome

BMJ Case Rep. 2011 Sep 28:2011:bcr0820114605. doi: 10.1136/bcr.08.2011.4605.


Touraine-Solente-Gole' syndrome, also known as pachydermoperiostosis or primary hypertrophic osteoarthropathy is a rare familial disorder generally seen in males. Although it presents with characteristic morphological and radiological features, this is an uncommon diagnosis and is entertained only once other causes of secondary hypertrophic osteoarthropathy are carefully excluded.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Bone Density Conservation Agents / therapeutic use
  • Diagnosis, Differential
  • Diphosphonates / therapeutic use
  • Humans
  • Imidazoles / therapeutic use
  • Male
  • Osteoarthropathy, Primary Hypertrophic / diagnosis*
  • Osteoarthropathy, Primary Hypertrophic / drug therapy
  • Zoledronic Acid


  • Bone Density Conservation Agents
  • Diphosphonates
  • Imidazoles
  • Zoledronic Acid