Trends in regionalization of radical cystectomy in three large northeastern states from 1996 to 2009

Urol Oncol. 2013 Nov;31(8):1663-9. doi: 10.1016/j.urolonc.2012.04.018. Epub 2012 Jun 9.

Abstract

Objectives: To assess regionalization trends and short-term clinical outcomes in patients undergoing radical cystectomy for urothelial carcinoma.

Materials and methods: Using 1996-2009 discharge data from New York (NY), New Jersey (NJ) and Pennsylvania (PA), all patients ≥ 18 years with urothelial carcinoma undergoing cystectomy were identified using ICD-9 coding. We assigned hospital volume status by quintiles based on relative proportions of cystectomies performed on a per hospital basis in 1996; very low volume hospitals: 0-2 (VLVH), low: 3-4 (LVH), moderate: 5-8 (MVH), high: 9-31 (HVH), and very high: ≥ 32 (VHVH). Changes in the proportion of procedures performed by volume categories were assessed over time, and patient characteristics were compared between groups.

Results: A total of 14,404 patients met inclusion criteria. For each year increase from 1996 to 2009, the odds of having surgery performed at a VHVH increased by 22% (odds ratio [OR] 1.22, confidence interval [CI] 1.04-1.44). Patients undergoing surgery at a VHVH were less likely to be African American (OR 0.59 [CI 0.39-0.91]), or insured through Medicaid (OR 0.65 [CI 0.50-0.84]) or Medicare (OR 0.84 [CI 0.75-0.94]). Controlling for year treated, total procedures performed, and patient characteristics, median hospital length of stay (HLOS) was shorter (median difference -0.89 days [CI -1.12 to -0.66]), and patients were significantly less likely to die during their hospital stay if treated at a VHVH compared with a VLVH (OR 0.33 [CI 0.22-0.49]).

Conclusions: There has been extensive regionalization of cystectomy to VHVHs in NY, NJ, and PA since 1996. Despite apparent improvements in mortality and HLOS in patients treated at higher volume centers in our sample, future investigations more rigorously adjusting for hospital structural characteristics and patient severity are necessary to confirm these findings. Disparities in access to VHVH care are still evident and must be addressed.

Keywords: Centralization; Cystectomy; Mortality; Regionalization; Urothelial carcinoma; Volume-outcomes.

MeSH terms

  • African Americans / statistics & numerical data
  • Aged
  • Aged, 80 and over
  • Asian Continental Ancestry Group / statistics & numerical data
  • Carcinoma, Transitional Cell / ethnology
  • Carcinoma, Transitional Cell / surgery*
  • Cystectomy / methods
  • Cystectomy / statistics & numerical data*
  • Cystectomy / trends
  • European Continental Ancestry Group / statistics & numerical data
  • Female
  • Healthcare Disparities / statistics & numerical data
  • Humans
  • Indians, North American / statistics & numerical data
  • International Classification of Diseases / statistics & numerical data
  • Length of Stay
  • Logistic Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • New Jersey
  • New York
  • Patient Discharge / statistics & numerical data*
  • Pennsylvania
  • Urinary Bladder Neoplasms / ethnology
  • Urinary Bladder Neoplasms / surgery*