Hepatic adenomatosis may mimic metastatic lesions of liver with 18F-FDG PET/CT

Clin Nucl Med. 2012 Jul;37(7):697-8. doi: 10.1097/RLU.0b013e3182443ced.


Hepatic adenomatosis is an uncommon benign neoplasm, with the presence of multiple adenomas (generally more than 4) within the liver. A 52-year-old woman presented with multiple (>10) solid liver lesions detected with abdominal ultrasonography and verified with magnetic resonance imaging (MRI). Subsequently, F-18 FDG PET/CT demonstrated increased uptake in these lesions. Histology revealed hepatic adenomatosis. F-18 FDG PET/CT cannot reliably differentiate hepatic adenomas from malignant processes on the basis of uptake.

Publication types

  • Case Reports

MeSH terms

  • Adenoma / diagnostic imaging*
  • Diagnosis, Differential
  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Liver / diagnostic imaging
  • Liver / pathology*
  • Liver Neoplasms / diagnostic imaging*
  • Liver Neoplasms / pathology
  • Middle Aged
  • Multimodal Imaging*
  • Neoplasm Metastasis
  • Positron-Emission Tomography*
  • Tomography, X-Ray Computed*
  • Whole Body Imaging


  • Fluorodeoxyglucose F18