ABC1K atypical kinases in plants: filling the organellar kinase void

Trends Plant Sci. 2012 Sep;17(9):546-55. doi: 10.1016/j.tplants.2012.05.010. Epub 2012 Jun 11.

Abstract

Surprisingly few protein kinases have been demonstrated in chloroplasts or mitochondria. Here, we discuss the activity of bc(1) complex kinase (ABC1K) protein family, which we suggest locate in mitochondria and plastids, thus filling the kinase void. The ABC1Ks are atypical protein kinases and their ancestral function is the regulation of quinone synthesis. ABC1Ks have proliferated from one or two members in non-photosynthetic organisms to more than 16 members in algae and higher plants. In this review, we reconstruct the evolutionary history of the ABC1K family, provide a functional domain analysis for angiosperms and a nomenclature for ABC1Ks in Arabidopsis (Arabidopsis thaliana), rice (Oryza sativa) and maize (Zea mays). Finally, we hypothesize that targets of ABC1Ks include enzymes of prenyl-lipid metabolism as well as components of the organellar gene expression machineries.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amino Acid Motifs
  • Benzoquinones / metabolism
  • Evolution, Molecular
  • Gene Expression Regulation, Enzymologic
  • Gene Expression Regulation, Plant / genetics
  • Magnoliopsida / enzymology*
  • Magnoliopsida / genetics
  • Magnoliopsida / ultrastructure
  • Mitochondria / enzymology*
  • Multigene Family
  • Phylogeny
  • Plant Proteins / genetics
  • Plant Proteins / metabolism
  • Plastids / enzymology*
  • Protein Kinases / genetics*
  • Protein Kinases / metabolism
  • Protein Structure, Tertiary
  • Yeasts / enzymology
  • Yeasts / genetics

Substances

  • Benzoquinones
  • Plant Proteins
  • quinone
  • Protein Kinases