Point-prevalence study of inappropriate antibiotic use at a tertiary Australian hospital

Intern Med J. 2012 Jun;42(6):719-21. doi: 10.1111/j.1445-5994.2012.02809.x.


A point-prevalence study at a tertiary Australian hospital found 199 of 462 inpatients (43%) to be receiving antibiotic therapy. Forty-seven per cent of antibiotic use was discordant with guidelines or microbiological results and hence considered inappropriate. Risk factors for inappropriate antibiotic prescribing included bone/joint infections, the absence of infection, creatinine level >120 µmol/L, carbapenem or macrolide use and being under the care of the aged care/rehabilitation team. In the setting of finite antimicrobial stewardship resources, identification of local determinants for inappropriate antibiotic use may enable more targeted interventions.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Creatinine / blood
  • Humans
  • Inappropriate Prescribing*
  • Multivariate Analysis
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Risk Factors
  • Western Australia


  • Anti-Bacterial Agents
  • Creatinine