Modeling brain disease in a dish: really?

Cell Stem Cell. 2012 Jun 14;10(6):642-645. doi: 10.1016/j.stem.2012.05.008.


Cellular programming and reprogramming technology (CPART) presents a novel approach for understanding disease progression and mechanism. In addition, CPART provides an innovative opportunity for developing diagnostic tools and novel drug candidates for therapy. In this Forum, we will discuss obstacles and solutions for modeling brain disease using CPART.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Brain Diseases / therapy*
  • Disease Models, Animal*
  • Humans
  • Regenerative Medicine / methods*
  • Stem Cells / cytology*
  • Stem Cells / physiology*
  • Tissue Engineering