Induced pluripotent stem cells: past, present, and future

Cell Stem Cell. 2012 Jun 14;10(6):678-684. doi: 10.1016/j.stem.2012.05.005.


The development of iPSCs reflected the merging of three major scientific streams and has in turn led to additional new branches of investigation. However, there is still debate about whether iPSCs are functionally equivalent to ESCs. This question should be answered only by science, not by politics or business.

MeSH terms

  • Animals
  • Cell Differentiation*
  • Humans
  • Induced Pluripotent Stem Cells / cytology*
  • Induced Pluripotent Stem Cells / physiology*
  • Induced Pluripotent Stem Cells / transplantation