Extracorporeal membrane oxygenation support of a severe metabolic crisis in a child with methylmalonic acidemia

ASAIO J. 2012 Jul-Aug;58(4):438-9. doi: 10.1097/MAT.0b013e31825a223c.


A 9-year-old female, with mut phenotype of methylmalonic acidemia who developed severe vasoplegic shock during a metabolic crisis, was successfully supported with venoarterial extracorporeal membrane oxygenation.

Publication types

  • Case Reports

MeSH terms

  • Amino Acid Metabolism, Inborn Errors / genetics*
  • Amino Acid Metabolism, Inborn Errors / pathology*
  • Child
  • Extracorporeal Membrane Oxygenation*
  • Female
  • Humans
  • Methylmalonic Acid / metabolism
  • Phenotype
  • Respiratory Insufficiency / etiology
  • Treatment Outcome
  • Vasoplegia / etiology


  • Methylmalonic Acid

Supplementary concepts

  • Methylmalonic acidemia