Peripheral giant cell granuloma associated with dental implants: clinical case and literature review

J Oral Implantol. 2012 Sep;38 Spec No:527-32. doi: 10.1563/AAID-JOI-D-11-00143. Epub 2012 Jun 19.


Peripheral giant cell granuloma (PGCG) associated to dental implants is a very infrequent peri-implant soft-tissue complication, with only 11 cases recorded in the literature to date. The present study describes a 54-year-old woman presenting a swelling of the alveolar margin in the fourth quadrant in relation to a fixed prosthesis cemented over implants. Treatment consisted of complete resection of the lesion with implantoplasty of the exposed implant threads. The diagnosis of PGCG was confirmed by histological study, and no relapse has been recorded after 12 months of follow-up.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Dental Implants / adverse effects*
  • Dental Prosthesis, Implant-Supported / adverse effects*
  • Denture, Partial, Fixed / adverse effects*
  • Female
  • Follow-Up Studies
  • Gingival Diseases / etiology
  • Gingival Diseases / pathology*
  • Gingival Diseases / surgery
  • Granuloma, Giant Cell / etiology
  • Granuloma, Giant Cell / pathology*
  • Granuloma, Giant Cell / surgery
  • Humans
  • Middle Aged
  • Oral Surgical Procedures / methods
  • Treatment Outcome


  • Dental Implants