The cognitive neuroscience of ageing

Nat Rev Neurosci. 2012 Jun 20;13(7):491-505. doi: 10.1038/nrn3256.


The availability of neuroimaging technology has spurred a marked increase in the human cognitive neuroscience literature, including the study of cognitive ageing. Although there is a growing consensus that the ageing brain retains considerable plasticity of function, currently measured primarily by means of functional MRI, it is less clear how age differences in brain activity relate to cognitive performance. The field is also hampered by the complexity of the ageing process itself and the large number of factors that are influenced by age. In this Review, current trends and unresolved issues in the cognitive neuroscience of ageing are discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aging*
  • Brain / anatomy & histology
  • Brain / physiology*
  • Cognition / physiology*
  • Humans
  • Male
  • Neurosciences*