Cancer cells use exosomes as tools to manipulate immunity and the microenvironment

Oncoimmunology. 2012 Jan 1;1(1):78-80. doi: 10.4161/onci.1.1.17826.


Exosomes are small vesicles secreted in relative abundance by cancer cells, which may prove useful as disease markers. However, exosomes also exhibit potent functions; modulating the behavior of immune- and other cells. Bridging our understanding of their molecular phenotype and functional mechanisms will provide key insight into their importance in cancer.