Modular organization of the mammalian Golgi apparatus

Curr Opin Cell Biol. 2012 Aug;24(4):467-74. doi: 10.1016/ Epub 2012 Jun 20.


The Golgi apparatus is essential for post-translational modifications and sorting of proteins in the secretory pathway. In addition, it further performs a broad range of specialized functions. This functional diversity is achieved by combining basic morphological modules of cisternae into higher ordered structures. Linking cisternae into stacks that are further connected through tubules into a continuous Golgi ribbon greatly increases its efficiency and expands its repertoire of functions. During cell division, the different modules of the Golgi are inherited by different mechanisms to maintain its functional and morphological composition.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Golgi Apparatus / chemistry*
  • Golgi Apparatus / metabolism*
  • Mammals