Incidence of glistenings with the latest generation of yellow-tinted hydrophobic acrylic intraocular lenses

J Cataract Refract Surg. 2012 Jul;38(7):1140-6. doi: 10.1016/j.jcrs.2012.01.031.


Purpose: To evaluate the incidence of glistenings in a large series of consecutive eyes with a blue light-filtering hydrophobic acrylic intraocular lens (IOL) and the relationship with parameters such as age, sex, follow-up length, and corrected distance visual acuity (CDVA).

Setting: Service d'Ophtalmologie, Centre Hospitalier et Universitaire Bordeaux, Bordeaux, France.

Design: Cross-sectional study.

Methods: This study included 111 eyes of 74 patients (age range 33 to 86 years). All cases had cataract surgery with Acrysof SN60WF monofocal IOL implantation and had a routine postoperative examination between March 2011 and June 2011. The incidence and severity of glistenings were evaluated with the slitlamp. Also evaluated was their relationship with age, sex, follow-up length, IOL power, and CDVA. Glistenings were subjectively graded (0 = absent; 1 = moderate; 2 = dense).

Results: Glistenings occurred in 96 eyes (86.5%). Glistenings were of grade 1 severity in 45 eyes (40.5%) and of grade 2 severity in 51 eyes (45.9%). The follow-up was significantly longer in eyes with grade 2 glistenings (P ≤ .01). A limited, but significant, correlation was found between glistening severity and length of follow-up (r = 0.32, P<.01). Although there was a trend toward decreased visual acuities at higher glistening grades (r = 0.22, P = .01), there were no significant differences in CDVA between the glistening severity groups (P = .14).

Conclusions: Glistenings were common in eyes with the blue light-filtering hydrophobic acrylic IOL and increased over time.

Financial disclosure: No author has a financial or proprietary interest in any material or method mentioned.

MeSH terms

  • Acrylic Resins*
  • Adult
  • Aged
  • Aged, 80 and over
  • Cataract Extraction
  • Cross-Sectional Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Lens Implantation, Intraocular
  • Lenses, Intraocular*
  • Male
  • Middle Aged
  • Prosthesis Failure*
  • Retrospective Studies
  • Time Factors
  • Vacuoles*
  • Vision Disorders / etiology
  • Vision Disorders / physiopathology
  • Visual Acuity / physiology


  • Acrylic Resins