Non-apoptotic functions of cell death effectors in inflammation and innate immunity

Microbes Infect. 2012 Nov;14(14):1241-53. doi: 10.1016/j.micinf.2012.06.005. Epub 2012 Jun 21.


Innate immunity and cell death are essential host defense mechanisms. Mounting evidence reveals that these processes are closely linked. The aim of this review is to highlight the close relationship between the pathways governing these processes, particularly how regulators of cell death control the induction of the innate immune response.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Death / immunology
  • Humans
  • Immunity, Innate / physiology*
  • Inflammation / immunology*