Psychological wellbeing and quality of life in amyotrophic lateral sclerosis: a review

Int J Psychol. 2013;48(3):194-205. doi: 10.1080/00207594.2012.691977. Epub 2012 Jun 25.


Amyotrophic lateral sclerosis is a fatal neurodegenerative disease with a progressive and rapid course that, so far, cannot be stopped or reversed. The psychological impact of the disease is huge, on both patients and caregivers. This review summarizes studies that have investigated quality of life, depression, anxiety, pain, spiritual and existential issues, hope, and hopelessness in the ALS field, with attention to both patients and their caregivers. Psychological support and the possible role of psychologists in the ALS field are also discussed.

Publication types

  • Review

MeSH terms

  • Amyotrophic Lateral Sclerosis / psychology*
  • Anxiety
  • Caregivers / psychology
  • Depression
  • Emotions
  • Existentialism
  • Humans
  • Pain
  • Quality of Life*
  • Social Support
  • Spirituality