NHLBI clinical trials workshop: an executive summary

Stat Med. 2012 Nov 10;31(25):2938-43. doi: 10.1002/sim.5406. Epub 2012 Jun 26.


On September 13-14, 2010, the National Heart, Lung and Blood Institute (NHLBI) organized a workshop: 'Clinical Trials: Past, Present and Future'. The workshop covered many areas in clinical trials, including the history of clinical trials at NHLBI, Bayesian clinical trials, surrogate endpoints, reporting clinical trials, handling missing data, flexible designs and adaptive trials, personalized medicine and genomic clinical trials, and comparative effectiveness research. In this report, we summarize the main discussions and conclusions based on the presentations of the invited speakers at the workshop.

Publication types

  • Historical Article

MeSH terms

  • Clinical Trials as Topic* / history
  • Clinical Trials as Topic* / methods
  • Clinical Trials as Topic* / statistics & numerical data
  • History, 20th Century
  • Humans
  • National Heart, Lung, and Blood Institute (U.S.)*
  • Randomized Controlled Trials as Topic / trends
  • Research Personnel / education*
  • United States