Experimental spectro-angular mapping of light distribution in turbid media

J Biomed Opt. 2012 Jun;17(6):067007. doi: 10.1117/1.JBO.17.6.067007.

Abstract

We present a new approach to the analysis of radiance in turbid media. The approach combines data from spectral, angular and spatial domains in a form of spectro-angular maps. Mapping provides a unique way to visualize details of light distribution in turbid media and allows tracking changes with distance. Information content of experimental spectro-angular maps is verified by a direct comparison with simulated data when an analytical solution of the radiative transfer equation is used. The findings deepen our understanding of the light distribution in a homogenous turbid medium and provide a first step toward applying the spectro-angular mapping as a diagnostic tool for tissue characterization.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Computer Simulation
  • Diagnostic Imaging / methods*
  • Equipment Design
  • Hemoglobins / metabolism
  • Humans
  • Light
  • Male
  • Monte Carlo Method
  • Nephelometry and Turbidimetry / methods*
  • Phantoms, Imaging
  • Photons
  • Prostate / pathology
  • Radiometry / methods
  • Reproducibility of Results
  • Scattering, Radiation
  • Spectrophotometry / methods

Substances

  • Hemoglobins