Proteomic updates on sepsis

Rev Assoc Med Bras (1992). 2012 May-Jun;58(3):376-82.
[Article in English, Portuguese]


The increased knowledge regarding proteomic analysis techniques has allowed for better understanding of the molecular bases related to the identification of cell signaling, modifying protein, and post-translational modification pathways, in addition to the characterization of specific biological markers. Thus, documenting certain proteins expressed in sepsis is a promising approach to elucidate pathophysiological, diagnostic, therapeutic, and prognostic aspects in this condition with a purpose of applying them to clinical practice. Although the studies are still preliminary, proteomics may offer good benefits for the better management of septic patients. Thus, this article aims to introduce a short review of the applications of proteomic studies to sepsis.

Publication types

  • Review

MeSH terms

  • Biomarkers / metabolism
  • Humans
  • Prognosis
  • Proteomics / methods*
  • Sepsis / diagnosis*
  • Sepsis / genetics
  • Sepsis / metabolism


  • Biomarkers