Quorum Sensing and Expression of Virulence in Pectobacteria

Sensors (Basel). 2012;12(3):3327-49. doi: 10.3390/s120303327. Epub 2012 Mar 8.

Abstract

Quorum sensing (QS) is a population density-dependent regulatory mechanism in which gene expression is coupled to the accumulation of a chemical signaling molecule. QS systems are widespread among the plant soft-rotting bacteria. In Pectobacterium carotovorum, at least two QS systems exist being specified by the nature of chemical signals involved. QS in Pectobacterium carotovorum uses N-acylhomoserine lactone (AHL) based, as well as autoinducer-2 (AI-2) dependent signaling systems. This review will address the importance of the QS in production of virulence factors and interaction of QS with other regulatory systems in Pectobacterium carotovorum.

Keywords: N-acylhomoserine lactone; Pectobacterium; autoinductor 2; quorum sensing; virulence.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • 4-Butyrolactone / analogs & derivatives
  • 4-Butyrolactone / metabolism
  • Gene Expression Regulation, Bacterial
  • Homoserine / analogs & derivatives
  • Homoserine / metabolism
  • Lactones / metabolism
  • Pectobacterium carotovorum / metabolism*
  • Pectobacterium carotovorum / pathogenicity
  • Quorum Sensing*
  • Signal Transduction
  • Virulence

Substances

  • Lactones
  • N-octanoylhomoserine lactone
  • homoserine lactone
  • Homoserine
  • 4-Butyrolactone