Deciphering membrane protein structures from protein sequences

Genome Biol. 2012 Jun 27;13(6):160. doi: 10.1186/gb-2012-13-6-160.


Co-evolving positions within protein sequences have been used as spatial constraints to develop a computational approach for modeling membrane protein structures.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Computational Biology
  • Humans
  • Membrane Proteins / chemistry*
  • Models, Molecular
  • Protein Conformation*


  • Membrane Proteins