Abstract
Comment on: Freed-Pastor WA, et al. Cell 2012; 148:244-58 and Ginestier C, et al. Stem Cells 2012; 1327-37.
MeSH terms
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Alkyl and Aryl Transferases / antagonists & inhibitors
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Alkyl and Aryl Transferases / metabolism
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Animals
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Cyclin-Dependent Kinase Inhibitor p27 / metabolism
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Mevalonic Acid / metabolism*
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Mice
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Neoplastic Stem Cells / enzymology
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Neoplastic Stem Cells / metabolism*
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Tumor Suppressor Protein p53 / genetics
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Tumor Suppressor Protein p53 / metabolism*
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rhoA GTP-Binding Protein / metabolism
Substances
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Tumor Suppressor Protein p53
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Cyclin-Dependent Kinase Inhibitor p27
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Alkyl and Aryl Transferases
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geranylgeranyltransferase type-I
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rhoA GTP-Binding Protein
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Mevalonic Acid