Purpose: Laparoscopic myomectomy during pregnancy is indicated when symptoms related to uterine myomas persist despite pharmacologic therapy; however, currently there is very little information concerning its safety.
Methods: We report three cases of antepartum laparoscopic myomectomy performed to manage complicated myomas requiring surgical intervention.
Results: In particular, we report for the first time in literature the laparoscopic removal of two myomas in a patient during a single surgery performed in the 19th week of pregnancy followed by additional multiple myomectomy at the time of the cesarean section. All surgeries were without complication.
Conclusions: Our experience suggests that laparoscopic myomectomy may be performed safely during pregnancy; even more studies are needed to establish the exact rate of adverse events.