Neglected infections of poverty in Texas and the rest of the United States: management and treatment options

Clin Pharmacol Ther. 2012 Aug;92(2):170-81. doi: 10.1038/clpt.2012.85. Epub 2012 Jul 4.


In the poorest regions of the United States, especially along the Gulf Coast and in South Texas, are a group of endemic parasitic and related infections known as the neglected infections of poverty. Such infections are characterized by their chronicity, disabling features, and disproportionate impact on the estimated 46 million people who live below the U.S. poverty line. Today more Americans live in poverty than ever before in the half-century that the Census Bureau has been recording poverty rates. In association with that poverty, a group of major neglected infections of poverty have emerged in the United States. Here we describe the major neglected infections of poverty in the United States, with a brief overview of their significant epidemiological features, their links with poverty, and our approaches to their diagnosis, management, and treatment.

MeSH terms

  • Arbovirus Infections / therapy
  • Chagas Disease / therapy
  • Cysticercosis / therapy
  • Dengue / therapy
  • Disease Management*
  • Humans
  • Parasitic Diseases / epidemiology
  • Parasitic Diseases / therapy*
  • Poverty Areas*
  • Strongylida Infections / therapy
  • Texas / epidemiology
  • Toxocariasis / therapy
  • United States / epidemiology
  • Virus Diseases / epidemiology
  • Virus Diseases / therapy*
  • West Nile Fever / therapy