Fungal hemolysins

Med Mycol. 2013 Jan;51(1):1-16. doi: 10.3109/13693786.2012.698025. Epub 2012 Jul 9.

Abstract

Hemolysins are a class of proteins defined by their ability to lyse red cells but have been described to exhibit pleiotropic functions. These proteins have been extensively studied in bacteria and more recently in fungi. Within the last decade, a number of studies have characterized fungal hemolysins and revealed a fascinating yet diverse group of proteins. The purpose of this review is to provide a synopsis of the known fungal hemolysins with an emphasis on those belonging to the aegerolysin protein family. New insight and perspective into fungal hemolysins in biotechnology and health are additionally presented.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Biotechnology
  • Fungal Proteins / metabolism*
  • Fungi / metabolism*
  • Fungi / pathogenicity
  • Health
  • Hemolysin Proteins / metabolism*
  • Hemolysis / physiology
  • Virulence Factors / metabolism

Substances

  • Fungal Proteins
  • Hemolysin Proteins
  • Virulence Factors
  • aegerolysin