Catatonic disorder due to a general medical or psychiatric condition

J Neuropsychiatry Clin Neurosci. 2012 Spring;24(2):198-207. doi: 10.1176/appi.neuropsych.11060120.


Identification of individuals with catatonic disorder secondary to a general medical condition (CD-GMC) may affect both acute and long-term patient management. The authors performed a 20-year retrospective cohort analysis of all patients meeting DSM-IV-TR criteria for catatonic subtypes seen at our institution. Encephalitis was the most common etiologic diagnosis among patients with CD-GMC, and lumbar puncture the test most likely to affect acute management. Univariate logistic-regression analysis utilizing Bonferroni correction for multiple comparisons yielded absence of a psychiatric history and history of clinical seizure as variables increasing the likelihood of a diagnosis of CD-GMC. Prospective evaluation across a larger patient series will be required to better identify patients with catatonia who would benefit from neurologic evaluation.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Catatonia / diagnosis
  • Catatonia / epidemiology*
  • Cohort Studies
  • Comorbidity
  • Electroencephalography / methods
  • Electroencephalography / psychology
  • Epilepsy / diagnosis
  • Epilepsy / epidemiology*
  • Female
  • Humans
  • Magnetic Resonance Imaging / methods
  • Magnetic Resonance Imaging / psychology
  • Male
  • Mental Disorders / diagnosis
  • Mental Disorders / epidemiology*
  • Middle Aged
  • Minnesota / epidemiology
  • Neuroimaging / methods
  • Neuroimaging / psychology*
  • Psychiatric Status Rating Scales / statistics & numerical data
  • Risk Factors
  • Spinal Puncture / adverse effects