Orthokeratology vs. spectacles: adverse events and discontinuations

Optom Vis Sci. 2012 Aug;89(8):1133-9. doi: 10.1097/OPX.0b013e318263c5af.

Abstract

Purpose: To assess the relative clinical success of orthokeratology contact lenses (OK) and distance single-vision spectacles (SV) in children in terms of incidences of adverse events and discontinuations over a 2-year period.

Methods: Sixty-one subjects 6 to 12 years of age with myopia of - 0.75 to - 4.00DS and astigmatism ≤1.00DC were prospectively allocated OK or SV correction. Subjects were followed at 6-month intervals and advised to report to the clinic immediately should adverse events occur. Adverse events were categorized into serious, significant, and non-significant. Discontinuation was defined as cessation of lens wear for the remainder of the study.

Results: Thirty-one children were corrected with OK and 30 with SV. A higher incidence of adverse events was found with OK compared with SV (p < 0.001). Nine OK subjects experienced 16 adverse events (7 significant and 9 non-significant). No adverse events were found in the SV group. Most adverse events were found between 6 and 12 months of lens wear, with 11 solely attributable to OK wear. Significantly more discontinuations were found with SV in comparison with OK (p < 0.05).

Conclusions: The relatively low incidence of adverse events and discontinuations with OK is conducive for the correction of myopia in children with OK contact lenses.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Astigmatism / physiopathology
  • Astigmatism / therapy*
  • Child
  • Contact Lenses, Hydrophilic / adverse effects*
  • Corneal Diseases / epidemiology
  • Corneal Diseases / etiology*
  • Eyeglasses / adverse effects*
  • Follow-Up Studies
  • Humans
  • Incidence
  • Myopia / physiopathology
  • Myopia / therapy*
  • Orthokeratologic Procedures / adverse effects*
  • Orthokeratologic Procedures / methods
  • Prospective Studies
  • Refraction, Ocular
  • Risk Factors
  • Spain / epidemiology