Microfluidic cell volume sensor with tunable sensitivity

Lab Chip. 2012 Sep 7;12(17):3016-9. doi: 10.1039/c2lc40357a. Epub 2012 Jul 11.

Abstract

We report the fabrication and validation of a microfluidic cell volume sensor integrated on a multi-layered polydimethylsiloxane (PDMS) microchip with a tunable detection volume for dynamic control of sensitivity, enabling the detection of individual Escherichia coli and microparticles.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Size*
  • Dimethylpolysiloxanes / chemistry
  • Electrochemical Techniques
  • Electrodes
  • Electrolytes / chemistry
  • Escherichia coli / isolation & purification
  • Microfluidic Analytical Techniques / instrumentation
  • Microfluidic Analytical Techniques / methods*
  • Microspheres
  • Signal-To-Noise Ratio

Substances

  • Dimethylpolysiloxanes
  • Electrolytes
  • baysilon