Long-term follow-up of deep brain stimulation for refractory obsessive-compulsive disorder

Psychiatry Res. 2012 Dec 30;200(2-3):1067-70. doi: 10.1016/j.psychres.2012.06.018. Epub 2012 Jul 9.


We studied the 2-year outcome of deep-brain stimulation at the ventral anterior limb of the internal capsule and ventral striatum for 4 patients with treatment-resistant OCD. There were prolonged improvement of obsessive-compulsive symptoms and depressive symptoms along with notable functional improvement in all participants with no battery depletion.

MeSH terms

  • Adolescent
  • Adult
  • Basal Ganglia / physiopathology*
  • Deep Brain Stimulation*
  • Female
  • Follow-Up Studies
  • Humans
  • Internal Capsule / physiopathology*
  • Male
  • Middle Aged
  • Obsessive-Compulsive Disorder / physiopathology
  • Obsessive-Compulsive Disorder / therapy*
  • Treatment Outcome