The investigation and management of hirsutism

J Fam Plann Reprod Health Care. 2012 Jul;38(3):182-6. doi: 10.1136/jfprhc-2011-100175.

Abstract

Excess male-pattern body hair in women is a very common and psychologically damaging condition. Although its cause is usually a chronic and benign disorder (most commonly polycystic ovary syndrome) it may rarely be an indication of a more serious endocrine disease such as Cushing syndrome or an androgen-secreting tumour. Investigations do not usually need to be extensive, but effective management is important, irrespective of cause, for what can be a debilitating symptom. Specific treatment of any underlying disease is important but in most cases treatment is empirical; it may simply involve physical hair removal, ideally by electrolysis or laser treatment. However, endocrine therapy to suppress androgen production and/or action is desirable in many, if not most, cases.

MeSH terms

  • Adrenal Glands / metabolism
  • Androgen Antagonists / therapeutic use
  • Androgens / blood
  • Androgens / metabolism*
  • Contraceptives, Oral, Hormonal / therapeutic use
  • Eflornithine / therapeutic use
  • Endocrine System Diseases / complications
  • Female
  • Hirsutism / diagnosis
  • Hirsutism / etiology
  • Hirsutism / physiopathology*
  • Hirsutism / therapy*
  • Humans
  • Ovary / metabolism
  • Polycystic Ovary Syndrome / complications
  • Polycystic Ovary Syndrome / therapy
  • Testosterone / metabolism

Substances

  • Androgen Antagonists
  • Androgens
  • Contraceptives, Oral, Hormonal
  • Testosterone
  • Eflornithine