High-velocity intermittent running: effects of beta-alanine supplementation

J Strength Cond Res. 2012 Oct;26(10):2798-805. doi: 10.1519/JSC.0b013e318267922b.


The use of β-alanine in sport is widespread. However, the effects across all sport activities are inconclusive. The purpose of this study was to evaluate the effects of β-alanine supplementation on high-intensity running performance and critical velocity (CV) and anaerobic running capacity (ARC). Fifty recreationally trained men were randomly assigned, in a double-blind fashion, to a β-alanine group (BA, 2 × 800 mg tablets, 3 times daily; CarnoSyn; n = 26) or placebo group (PL, 2 × 800 mg maltodextrin tablets, 3 times daily; n = 24). A graded exercise test (GXT) was performed to establish peak velocity (PV). Three high-speed runs to exhaustion were performed at 110, 100, and 90% of PV, with 15 minutes of rest between bouts. The distances achieved were plotted over the time to exhaustion (TTE). Linear regression was used to determine the slope (CV) and y-intercept (ARC) of these relationships to assess aerobic and anaerobic performances, respectively. There were no significant treatment effects (p > 0.05) on CV or ARC for either men or women. Additionally, no TTE effects were evident for bouts at 90-110%PV lasting 1.95-5.06 minutes. There seems to be no ergogenic effect of β-alanine supplementation on CV, ARC, or high-intensity running lasting approximately 2-5 minutes in either men or women in the current study.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Anaerobic Threshold / drug effects
  • Anaerobic Threshold / physiology
  • Athletic Performance / physiology
  • Dietary Supplements*
  • Double-Blind Method
  • Exercise Test
  • Female
  • Humans
  • Male
  • Oxygen Consumption / drug effects
  • Oxygen Consumption / physiology
  • Physical Endurance / drug effects
  • Physical Endurance / physiology
  • Running / physiology*
  • Young Adult
  • beta-Alanine / administration & dosage*


  • beta-Alanine