Graphene oxide wrapping on squaraine-loaded mesoporous silica nanoparticles for bioimaging

J Am Chem Soc. 2012 Oct 24;134(42):17346-9. doi: 10.1021/ja305352d. Epub 2012 Jul 20.

Abstract

Squaraine dyes were loaded inside mesoporous silica nanoparticles, and the nanoparticle surfaces were then wrapped with ultrathin graphene oxide sheets, leading to the formation of a novel hybrid material. The hybrid exhibits remarkable stability and can efficiently protect the loaded dye from nucleophilic attack. The biocompatible hybrid is noncytotoxic and presents significant potential for application in fluorescence imaging in vitro.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocompatible Materials / chemistry
  • Biosensing Techniques*
  • Cyclobutanes / chemistry*
  • Fluorescent Dyes / chemistry
  • Graphite / chemical synthesis
  • Graphite / chemistry*
  • HeLa Cells
  • Humans
  • Microscopy, Fluorescence
  • Nanoparticles / chemistry*
  • Oxides / chemical synthesis
  • Oxides / chemistry*
  • Phenols / chemistry*
  • Porosity
  • Silicon Dioxide / chemistry*
  • Surface Properties

Substances

  • Biocompatible Materials
  • Cyclobutanes
  • Fluorescent Dyes
  • Oxides
  • Phenols
  • squaraine
  • Silicon Dioxide
  • Graphite